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Although various methods have been proposed for multi-label classification, most approaches still follow the feature learning mechanism of the single-label (multi-class) classification, namely, learning a shared image feature to classify multiple labels. However, we find this One-shared-Feature-for-Multiple-Labels (OFML) mechanism is not conducive to learning discriminative label features and makes the model non-robustness. For the first time, we mathematically prove that the inferiority of the OFML mechanism is that the optimal learned image feature cannot maintain high similarities with multiple classifiers simultaneously in the context of minimizing cross-entropy loss. To address the limitations of the OFML mechanism, we introduce the One-specific-Feature-for-One-Label (OFOL) mechanism and propose a novel disentangled label feature learning (DLFL) framework to learn a disentangled representation for each label. The specificity of the framework lies in a feature disentangle module, which contains learnable semantic queries and a Semantic Spatial Cross-Attention (SSCA) module. Specifically, learnable semantic queries maintain semantic consistency between different images of the same label. The SSCA module localizes the label-related spatial regions and aggregates located region features into the corresponding label feature to achieve feature disentanglement. We achieve state-of-the-art performance on eight datasets of three tasks, \ie, multi-label classification, pedestrian attribute recognition, and continual multi-label learning.