论文标题

一种新的分解,以解释因果关系的观测和随机研究中的异质性

A novel decomposition to explain heterogeneity in observational and randomized studies of causality

论文作者

Gilbert, Brian, Dıaz, Ivan, Rudolph, Kara E., Vo, Tat-Thang

论文摘要

本文介绍了一个新型的分解框架,以解释在不同研究中观察到的因果效应的异质性,考虑到观察和随机环境。我们提出了研究间异质性的形式分解,确定了整个研究的治疗效果的可变性来源。所提出的方法允许在各种假设下对因果参数进行稳健的估计,从而解决了治疗前协变量分布的差异,中介变量和结果机制。我们的方法通过仿真研究验证,并应用于移动到机会(MTO)研究的数据,证明了其实际相关性。这项工作有助于更广泛地理解多研究环境中因果推断,并在证据综合和决策中的潜在应用。

This paper introduces a novel decomposition framework to explain heterogeneity in causal effects observed across different studies, considering both observational and randomized settings. We present a formal decomposition of between-study heterogeneity, identifying sources of variability in treatment effects across studies. The proposed methodology allows for robust estimation of causal parameters under various assumptions, addressing differences in pre-treatment covariate distributions, mediating variables, and the outcome mechanism. Our approach is validated through a simulation study and applied to data from the Moving to Opportunity (MTO) study, demonstrating its practical relevance. This work contributes to the broader understanding of causal inference in multi-study environments, with potential applications in evidence synthesis and policy-making.

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