论文标题
交联半串联聚合物的自组装网络的结构特征和非线性流变学
Structural features and nonlinear rheology of self-assembled networks of cross-linked semiflexible polymers
论文作者
论文摘要
半灵性细丝的无序网络是生物学中的常见支持结构。熟悉的例子包括血凝块中的纤维基质，细菌生物膜以及植物，动物和真菌的细胞和组织的基本成分。尽管这些网络在生物材料中的无处不在，但我们对它们的结构特征与高应变敏感的机械性能之间的关系有限。在这项工作中，我们对连接器充分装饰的半融合细丝之间的交联成不可逆地形成产生的三维网络进行了模拟。我们表征了由简单扩散依赖性组装过程形成的网络的结构，并在有限温度下测量其相关的稳态流变特征，这些特征在涵盖应变延伸过渡的一系列应用prestrains范围内。我们量化了网络连通性对交联的可用性的依赖性，并详细介绍了线性弹性和非线性应变僵硬行为的相关连通性依赖性，并将比较与肌动蛋白凝胶的交叉链接浓度依赖性弹性的先前实验测量进行了比较。
Disordered networks of semiflexible filaments are common support structures in biology. Familiar examples include fibrous matrices in blood clots, bacterial biofilms, and essential components of cells and tissues of plants, animals, and fungi. Despite the ubiquity of these networks in biomaterials, we have only a limited understanding of the relationship between their structural features and highly strain-sensitive mechanical properties. In this work, we perform simulations of three-dimensional networks produced by the irreversible formation of crosslinks between linker-decorated semiflexible filaments. We characterize the structure of networks formed by a simple diffusion-dependent assembly process and measure their associated steady-state rheological features at finite temperature over a range of applied prestrains that encompass the strain-stiffening transition. We quantify the dependence of network connectivity on crosslinker availability and detail the associated connectivity dependence of both linear elasticity and nonlinear strain stiffening behavior, drawing comparisons with prior experimental measurements of the crosslinker concentration-dependent elasticity of actin gels.
