论文标题

冠状动脉和心肌空间数据的后处理

Post-processing of coronary and myocardial spatial data

论文作者

Mackenzie, Jay Aodh, Miller, Megan Jeanne, Hill, Nicholas, Olufsen, Mette

论文摘要

现实现象的数值模拟需要计算方案和计算域。在血流动力学的背景下,计算域是血管通过血管流动的网络。这样的网络包含数百万个串联和并行连接的容器。在整个网络中明确模拟血流是计算上不可行的。从单个猪左冠状动脉树中,我们开发了一个数据管道,以从代表部分冠状动脉树的图中获取心肌中血流动力学模拟的计算域。此外,使用与左心室的美国心脏协会分裂进行比较,我们开发了一种确定左心壁的哪个子区域更有可能通过给定的动脉灌注的方法。

Numerical simulations of real-world phenomena require a computational scheme and a computational domain. In the context of haemodynamics, the computational domain is the blood vessel network through which blood flows. Such networks contain millions of vessels that are joined in series and in parallel. It is computationally unfeasible to explicitly simulate blood flow throughout the network. From a single porcine left coronary arterial tree, we develop a data pipeline to obtain computational domains for haemodynamic simulations in the myocardium from a graph representing a partial coronary arterial tree. In addition, we develop a method to ascertain which subregions of the left-ventricular wall are more likely to be perfused via a given artery, using a comparison with the American Heart Association division of the left ventricle for validation.

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