论文标题
表面白质分析:一个有效的基于点云的深度学习框架,具有监督的对比度学习,以跨种群和DMRI收购的一致拖拉术进行分析
Superficial White Matter Analysis: An Efficient Point-cloud-based Deep Learning Framework with Supervised Contrastive Learning for Consistent Tractography Parcellation across Populations and dMRI Acquisitions
论文作者
论文摘要
扩散MRI拖拉术是一种高级成像技术,可以在体内映射大脑的白质连接。白质拟层将牵引力分类为簇或解剖学上有意义的区域。它可以量化和可视化全脑拖拉术。当前,大多数分析方法都集中在深白质(DWM)上,而由于其复杂性,较少的方法解决了浅表白质(SWM)。我们提出了一种新型的两阶段深度学习框架,表面白质分析(SUPWMA),该框架对全脑拖拉术的198个SWM簇进行了有效且一致的分析。一个基于点云的网络适应了我们的SWM分析任务,并且监督的对比学习可以使SWM的合理流线和离群值之间更具歧视性表示。我们将模型训练在大型拖拉机数据集上,包括来自标记的长和中范围(超过40毫米)SWM簇的简化样品和解剖学上难以置信的流线样本,并且我们对六个独立获取的不同年龄和健康状况(包括Neonantes and Neonates and Neonates and Neonates and Neonates and Neonates and Neonates and Neonate and Neonates and Nainate and Nainates and Nainates and Nainates and Nakecupupupupuppupupuping bainmpupuping bainmpupuped rabinempupy bainmpupy thaumers thaumers thaumors thumors taumors)进行了测试。与几种最先进的方法相比,SupWMA在所有数据集上获得了高度一致,准确的SWM分析结果,显示了整个健康和疾病的寿命良好的概括。另外,SUPWMA的计算速度比其他方法快得多。
Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts. It enables quantification and visualization of whole-brain tractography. Currently, most parcellation methods focus on the deep white matter (DWM), whereas fewer methods address the superficial white matter (SWM) due to its complexity. We propose a novel two-stage deep-learning-based framework, Superficial White Matter Analysis (SupWMA), that performs an efficient and consistent parcellation of 198 SWM clusters from whole-brain tractography. A point-cloud-based network is adapted to our SWM parcellation task, and supervised contrastive learning enables more discriminative representations between plausible streamlines and outliers for SWM. We train our model on a large-scale tractography dataset including streamline samples from labeled long- and medium-range (over 40 mm) SWM clusters and anatomically implausible streamline samples, and we perform testing on six independently acquired datasets of different ages and health conditions (including neonates and patients with space-occupying brain tumors). Compared to several state-of-the-art methods, SupWMA obtains highly consistent and accurate SWM parcellation results on all datasets, showing good generalization across the lifespan in health and disease. In addition, the computational speed of SupWMA is much faster than other methods.