论文标题
SARS-COV-2是一种新的科学怪人怪物病毒吗？
Is SARS-CoV-2 a new Frankenstein monster virus?
论文作者
论文摘要
严重的急性呼吸综合症冠状病毒2（SARS-COV-2）是一种新型的β冠状病毒属的病毒，起源于2019年中国武汉，导致Corona病毒疾病2019年大流行（Covid-19）全球世界。该属还包含SARS-COV（起源于2002 - 2003年中国）和MERS-COV（在沙特阿拉伯2012年发现）。 SARS-COV-2的核苷酸序列比MERS-COV更接近SARS-COV（大约80％的身份）。尽管有这些相似之处，但SARS-COV-2在其他冠状病毒中具有两个主要特征。第一个是高传染性速率，第二个是免疫反应逃避。较高的传播能力使该病毒以高死亡率和更多的经济损失而迅速在全球范围内传播。这篇综述将概述有关某些病毒和宿主细胞因子在SARS-COV-2的更高传播和传染性传播中的作用的当前知识。
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus of beta coronavirus genus originated in Wuhan, China in December 2019, resulted in the pandemic spread of Corona Virus Disease 2019 (COVID-19) worldwide. This genus also contains SARS-CoV (originated in China 2002-2003) and MERS-CoV (found in Saudi Arabia 2012). The nucleotide sequences of SARS-CoV-2 is closer to SARS-CoV (with approximately 80% identity) than to MERS-CoV. Despite these similarities, SARS-CoV-2 has two main features over the other coronaviruses. The first is the high contagious rate and the second is the immune response evasion. The higher transmission ability makes this virus quickly spread worldwide with a high mortality rate and more economic losses. This review will provide an overview of the current knowledge on the role of some viral and host cell factors in higher transmission and contagious spread of SARS-CoV-2.
