论文标题
观察到的和估计的Covid-19在意大利的患病率:是否可以从医疗拭子数据中估算总案例?
Observed and estimated prevalence of Covid-19 in Italy: Is it possible to estimate the total cases from medical swabs data?
论文作者
论文摘要
在当前的199年19日大流行期间,按照纯粹的便利性标准收集了官方数据,至少在早期阶段,它使患者的检查表现出明显的症状。然而,有很高比例的无症状患者的证据(例如,Aguilar等,2020; Chugthai等,2020; Li等,2020; Mizumoto等,2020a,2020b and 2020b and Yelin等,2020)。在这种情况下,为了估计受感染的实际数量(并估计致死率),应该有必要进行适当设计的样本调查,通过该调查可以计算包容性的可能性,从而绘制声音概率推断。一些研究人员提出了基于各种方法的总患病率的估计,包括流行病学模型,时间序列以及对早期流行病的国家收集的数据的分析(Brogi等人,2020年)。在本文中,我们建议通过重新批准Istituto Superiore diSanità发布的可用官方数据,以获取意大利人口更具代表性的样本,以估算意大利Covid-19的普遍性。重新加权是一种通常用于人为修改样品组成的程序,以获得与人群更相似的分布(Valliant等,2018)。在本文中,我们将使用官方数据的分层后分层,以获取使用年龄和性别作为分层后变量重新加权所必需的权重,从而获得更可靠的患病率和致死性的估计。
During the current Covid-19 pandemic in Italy, official data are collected with medical swabs following a pure convenience criterion which, at least in an early phase, has privileged the exam of patients showing evident symptoms. However, there are evidences of a very high proportion of asymptomatic patients (e. g. Aguilar et al., 2020; Chugthai et al, 2020; Li, et al., 2020; Mizumoto et al., 2020a, 2020b and Yelin et al., 2020). In this situation, in order to estimate the real number of infected (and to estimate the lethality rate), it should be necessary to run a properly designed sample survey through which it would be possible to calculate the probability of inclusion and hence draw sound probabilistic inference. Some researchers proposed estimates of the total prevalence based on various approaches, including epidemiologic models, time series and the analysis of data collected in countries that faced the epidemic in earlier time (Brogi et al., 2020). In this paper, we propose to estimate the prevalence of Covid-19 in Italy by reweighting the available official data published by the Istituto Superiore di Sanità so as to obtain a more representative sample of the Italian population. Reweighting is a procedure commonly used to artificially modify the sample composition so as to obtain a distribution which is more similar to the population (Valliant et al., 2018). In this paper, we will use post-stratification of the official data, in order to derive the weights necessary for reweighting them using age and gender as post-stratification variables thus obtaining more reliable estimation of prevalence and lethality.