论文标题
强大的宽带脂肪抑制变速箱T2制备模块，用于3T的心脏磁共振成像
A robust broadband fat suppressing phaser T2 preparation module for cardiac magnetic resonance imaging at 3T
论文作者
论文摘要
目的：设计新的T2制备（T2-PREP）模块，以便同时提供强大的脂肪抑制和有效的T2制备，而无需在3T处使用T2加权成像的额外的脂肪抑制模块。 Methods: The tip-down RF pulse of an adiabatic T2 preparation (T2-Prep) module was replaced by a custom-designed RF excitation pulse that induces a phase difference between water and fat, resulting in a simultaneous T2 preparation of water signals and the suppression of fat signals at the end of the module (now called a phaser adiabatic T2-Prep).使用数值模拟，体外和体内ECG触发的导航器的门控对人心脏，血液，心肌和脂肪含量比率以及使用这种方法使用这种方法的敏锐度与先前发表的常规Adiabatie Timbal抑制作用相比，相比使用拟议方法的不均匀性，同时保留水T2制备能力。与其他测试的方法相比，在幻影和体内MRA上获得的组织信号证实了这一点，它们显示出相似的血液和心肌SNR和心肌，并显着降低了脂肪SNR。结果，RCA的明显增加显着增加，并且在视觉上减少了运动伪像。结论：与常规技术相比，开发并实施了一种新型的脂肪抑制T2预制作方法，该方法证明了强大的脂肪抑制和增加的血管清晰度，同时保留其T2制备能力。
Purpose: Designing a new T2 preparation (T2-Prep) module in order to simultaneously provide robust fat suppression and efficient T2 preparation without requiring an additional fat suppression module for T2-weighted imaging at 3T. Methods: The tip-down RF pulse of an adiabatic T2 preparation (T2-Prep) module was replaced by a custom-designed RF excitation pulse that induces a phase difference between water and fat, resulting in a simultaneous T2 preparation of water signals and the suppression of fat signals at the end of the module (now called a phaser adiabatic T2-Prep). Using numerical simulations, in vitro and in vivo ECG-triggered navigator gated acquisitions of the human heart, the blood, myocardium and fat signal-to-noise ratio and right coronary artery (RCA) vessel sharpness using this approach were compared against previously published conventional adiabatic T2-Prep approaches Results: Numerical simulations predicted an increased fat suppression bandwidth and decreased sensitivity against transmit magnetic field inhomogeneities using the proposed approach, while preserving the water T2 preparation capabilities. This was confirmed by the tissue signals acquired on the phantom and the in vivo MRA, which show similar blood and myocardium SNR and CNR and significantly reduced fat SNR compared to the other methods tested. As a result, the RCA conspicuity was significantly increased and the motion artifacts were visually decreased. Conclusion: A novel fat-suppressing T2-preparation method was developed and implemented that demonstrated robust fat suppression and increased vessel sharpness compared with conventional techniques, while preserving its T2 preparation capabilities.
