论文标题
在细菌菌落中，限制引起的自组织
Confinement-induced self-organization in growing bacterial colonies
论文作者
论文摘要
我们研究了在限制下分裂的棒状细胞菌落中的全球比对的出现。使用分子动力学模拟和连续建模，我们证明了狭窄环境中的几何各向异性在正常应力中导致不平衡，这反过来又驱动了细胞的集体重排。这种行为至关重要地依赖于菌落在短时尺度上的固体机械响应，并且可以在主动流体动力学框架内回收细菌菌落，因为细菌菌落以麦克斯韦（Maxwell）胁迫弛豫为特征的粘弹性凝胶增长。
We investigate the emergence of global alignment in colonies of dividing rod-shaped cells under confinement. Using molecular dynamics simulations and continuous modeling, we demonstrate that geometrical anisotropies in the confining environment give rise to imbalance in the normal stresses, which, in turn, drives a collective rearrangement of the cells. This behavior crucially relies on the colony's solid-like mechanical response at short time scales and can be recovered within the framework of active hydrodynamics upon modeling bacterial colonies as growing viscoelastic gels characterized by Maxwell-like stress relaxation.
