论文标题
链接通过孔的易位：链接复杂性和大小的影响
Translocation of links through a pore: effects of link complexity and size
论文作者
论文摘要
我们已经使用Langevin动力学来通过狭窄的孔模拟连接的聚合物环的强制易位。对于固定尺寸（即固定的单体数量），易位时间取决于链接类型以及是否打结或未打结环。对于带有两个未结结的环的链接，环之间的交叉点可以减慢易位，并在交叉通过孔通过孔时导致延迟。结果落在一组相对平滑的曲线上，对于不同的链接家族，易位时间并不总是随着同一家族的交叉数量而增加。打结一个环时，结果取决于链接是质量还是复合材料，对于复合案例，它们取决于打结的环还是未打结的环首先进入孔。我们发现了3组分链接的类似情况，其中结果取决于链接是主要还是复合链接。这些结果有助于我们理解细丝之间的纠缠复杂性如何影响其易位动态，并且对于扩展纳米感应技术以探测这些系统的拓扑特性应该很有用。
We have used Langevin dynamics to simulate the forced translocation of linked polymer rings through a narrow pore. For fixed size (i.e. fixed number of monomers) the translocation time depends on the link type and on whether the rings are knotted or unknotted. For links with two unknotted rings, the crossings between the rings can slow down the translocation and are responsible for a delay as the crossings pass through the pore. The results fall on a set of relatively smooth curves for different link families with the translocation time not always increasing with crossings number within the same family. When one ring is knotted the results depend on whether the link is prime or composite and, for the composite case, they depend on whether the knotted or unknotted ring enters the pore first. We find a similar situation for 3-component links where the results depend on whether the link is prime or composite. These results contribute to our understanding of how the entanglement complexity between filaments impacts their translocation dynamics and should be useful for extending nanopore-sensing techniques to probe the topological properties of these systems.
